For the symmetry characteristics, only the first half of PSD is presented. Figure 3. Figure 4. Wavelet packets decomposition tree at level 3. Figure 5. Measures of prediction accuracy at the nucleotide level. Figure 6. Both methods employ the Code13 mapping method and all the other procedures are identical except whether denoising or not.
Table 1. Performance measures of five mapping methods for sequence F56F Figure 7. Exonic identification results of gene sequence F56F The red bold line segments represent the true exons that must be identified, the black thin line segments represent the predicted candidate exons, and the vertical heights of those line segments represent their optimal thresholds. The square shadow represents the missing true exon; the rectangle shadow represents the false predicted exon.
Figure 8. The distribution of exonic regions lengths in HRM The horizonal axis represents the exonic regions length, and the vertical axis represents the number of exonic regions. Table 2. Performance measures of five mapping methods for three benchmark datasets. Figure 9. ROC curves of different techniques for three benchmark datasets. References S. Nemati, M. Basiri, N. Ghasem-Aghaee, and M.
Marhon and S. Sagot, T. Schiex, and P. Song and H. Maji and D. Goel, S. Singh, and T. Saberkari, M. Shamsi, H. Heravi, and M. View at: Google Scholar J. Mena-Chalco, H. Carrer, Y. Zana, and R. Cesar Jr. Henderson, S. Salzberg, and K. View at: Google Scholar C. Ding and I. Tiwari, S. Ramachandran, A. Bhattacharya, S. Bhattacharya, and R. View at: Google Scholar R. Nini and S. Tsonis, J.
Elsner, and P. Chatzidimitriou-Dreismann and D. View at: Google Scholar H. Shamsi, M. Sedaaghi, and F. Rao, X. Lei, J. Guo, H. Huang, and Z. Vaidyanathan and B. View at: Google Scholar E. Ifeachor and B. Chakravarthy, A. Spanias, L. Iasemidis, and K. Akhtar, E. Ambikairajah, and J. Yan and T.
Choogn and H. View at: Google Scholar S. Xu, N. Chen, and B. Abbasi, A. Rostami, and G. Rogic, A. Mackworth, and F. View at: Google Scholar M. Burset and R. Kwan, B. Kwan, and J.
Abo-Zahhad, M. Ahmed, and S. Silverman and R. Achuthsanar and S. Akhtar, J. Epps, and E. Zhang and C. Florquin, Y. Saeys, S. Degroeve, P. Zhang and H. Lawson and R. View at: MathSciNet H. Lang and J. Zhao, J. Ma, S. Fan, and Z. View at: Google Scholar L. Wang, C. Liu, F. Bi, X. Bi, and K. Vong and P. View at: MathSciNet S. Xu, Research on the thresholds selection based on the bootstrap algorithm in gene-prediction [M. Kwan, and H. Li, C. Zhang, Z.
Shen, and X. Chung, S. Wadhawan, R. Szklarczyk, S. Pond, and A. View at: Publisher Site Google Scholar. More related articles.
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Received : 28 October Accepted : 03 December Issue Date : 01 March Anyone you share the following link with will be able to read this content:. Sorry, a shareable link is not currently available for this article. Provided by the Springer Nature SharedIt content-sharing initiative. BMC Genomics Nature Communications Neural Computing and Applications Scientific Reports Advanced search. Indels with a length divisible by three i.
Note that indels divisible by three may also cause a missense or nonsense variant if the the variant falls across two codons. However, if the length is not divisible by three, this will cause a frameshift where all codons downstream of the indel are shifted, often resulting in a malformed protein or nonsense-mediated decay.
Human genetic variation An introduction. Open Tree arrow-right-1 Course overview Search within this course What is genetic variation Open Tree arrow-right-1 What are variants, alleles and haplotypes?
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