Available from: www. Minutes of the rd medicines adverse reactions committee meeting — 10 September Medsafe, Medicine Datasheet, Management of suspected bacterial urinary infection in adults. Edinburgh: SIGN, Adult empirical antimicrobial treatment guidelines.
ADHB, NZF v Antibiotics: choices for common infections. Nitrofurantoin-induced pulmonary reaction involving respiratory symptoms: case report. Can J Hosp Pharm ;—5. Antimicrobial resistance data from hospital and community laboratories. ESR, Are our patients kidneys any different? Make a comment:. Please login to make a comment. This article is 6 years and 1 month old.
Chronic pulmonary reactions include malaise, dyspnoea, cough, and diffuse interstitial pneumonitis or fibrosis or both 1. If any of these pulmonary reactions occur, nitrofurantoin should be discontinued and the patient should be advised to seek medical attention.
Alimentary and skin reactions are mostly reported in the first week of nitrofurantoin use, whereas liver reactions generally occur after one month.
Respiratory and nervous system reactions are reported at all the time periods analysed Table 1. The reaction onset time by age group is shown in Table 2. As expected, the number of reports increases with the age of the patient, likely due to greater use and greater susceptibility to adverse reactions. Both acute and chronic reactions are reported in all age groups, with the exception of those aged under 20 years.
Pulmonary toxicity, hepatotoxicity, and hemolytic anemia are rather rare occurrences, and are often linked to prolonged treatments 6 months or longer. Cure rates and adverse reactions are similar to patients with normal renal function. Previous Next. By: Bryan D. Common question: Why not just prescribe 5 days nitrofurantoin for all patients with acute uncomplicated cystitis? Bio Twitter Facebook Latest Posts.
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